Auxiliary subunits: essential components of the voltage-gated calcium channel complex. Structure and regulation of voltage-gated Ca2+ channels. Phosphorylation of the AMPA receptor GluR1 subunit is required for synaptic plasticity and retention of spatial memory. Bidirectional synaptic plasticity regulated by phosphorylation of stargazin-like TARPs. Tomita, S., Stein, V., Stocker, T.J., Nicoll, R.A. Impaired regulation of synaptic strength in hippocampal neurons from GluR1-deficient mice. Acidic motif responsible for plasma membrane association of the voltage-dependent calcium channel beta1b subunit. Importance of the different beta subunits in the membrane expression of the alpha1A and alpha2 calcium channel subunits: studies using a depolarization-sensitive alpha1A antibody. Roles of a membrane-localized beta subunit in the formation and targeting of functional L-type Ca 2+ channels. A juvenile form of postsynaptic hippocampal long-term potentiation in mice deficient for the AMPA receptor subunit GluR-A. A new ER trafficking signal regulates the subunit stoichiometry of plasma membrane K(ATP) channels. Quality control in the endoplasmic reticulum. Interaction with the unfolded protein response reveals a role for stargazin in biosynthetic AMPA receptor transport. The multifarious hippocampal mossy fiber pathway: a review. Contrasting properties of two forms of long-term potentiation in the hippocampus. The synaptic activation of kainate receptors. Kainate receptors mediate a slow postsynaptic current in hippocampal CA3 neurons. Importance of AMPA receptors for hippocampal synaptic plasticity but not for spatial learning. Synapse-associated protein 97 selectively associates with a subset of AMPA receptors early in their biosynthetic pathway. N-glycosylation site tagging suggests a three transmembrane domain topology for the glutamate receptor GluR1. Protein oligomerization in the endoplasmic reticulum. Calcium channel gamma subunits provide insights into the evolution of this gene family. A cluster of three novel Ca2+ channel gamma subunit genes on chromosome 19q13.4: evolution and expression profile of the gamma subunit gene family. A family of gamma-like calcium channel subunits. Direct interactions between PSD-95 and stargazin control synaptic AMPA receptor number. Functional studies and distribution define a family of transmembrane AMPA receptor regulatory proteins. Stargazin regulates synaptic targeting of AMPA receptors by two distinct mechanisms. Impairment of AMPA receptor function in cerebellar granule cells of ataxic mutant mouse stargazer. Impaired cerebellar synapse maturation in waggler, a mutant mouse with a disrupted neuronal calcium channel gamma subunit. The mouse stargazer gene encodes a neuronal Ca 2+-channel gamma subunit. Synaptic transmission and plasticity in the absence of AMPA glutamate receptor GluR2 and GluR3.
Molecular organization of the postsynaptic specialization.
Postsynaptic organization and regulation of excitatory synapses. PDZ domains in synapse assembly and signalling. Receptor trafficking and the plasticity of excitatory synapses. Mammalian ionotropic glutamate receptors. AMPA receptor trafficking at excitatory synapses. Regulation of AMPA receptors during synaptic plasticity. AMPA receptor trafficking and synaptic plasticity.
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